Nonfunctioning tumor of the Langerhans' islets
نویسندگان
چکیده
منابع مشابه
Growth of the islets of Langerhans.
factor; here according to current concepts the pituitary growth hormone may play an important part. In the case of the "pre-diabetic fathers," the factor of inheritance must be the determining factor. Jackson contends that when a woman gives a history of having had several large babies, the diagnosis of a pre-diabetic state is justified to such an extent that treatment should be started before ...
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The juxtaglomerular cell tumor (JGCT) is a rare renal tumor characterized by excessive renin secretion causing intractable hypertension and hypokalemia. However, asymptomatic nonfunctioning JGCT is extremely rare. Here, we report a case of nonfunctioning JGCT in a 31-year-old woman. The patient presented with a left renal tumor without hypertension or hypokalemia. Under a clinical diagnosis of ...
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Insulin is released from the pancreas in pulses with a period of ~ 5 min. These oscillatory insulin levels are essential for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes. What coordinates the many islets of Langerhans throughout the pancreas to produce unified oscillations of insulin secretion? One hypothesis is that coordination is achieved through an insul...
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A small-for-dates male infant who developed acute metabolic acidosis shortly after birth had diabetes and died aged 40 hours. At necropsy there was an absence of any recognizable islets of Langerhans though lymphorecticular aggregates were found. This was the fourth child of healthy unrelated parents whose first child, also a male, died at 48 hours under similar circumstances. It is suggested t...
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The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes. Long-term islet graft survival has been achieved in a non-human primate pre-clinical model with a protocol of T-cell signaling blockade u...
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ژورنال
عنوان ژورنال: Acta chirurgica Iugoslavica
سال: 2002
ISSN: 0354-950X,2406-0887
DOI: 10.2298/aci0201081g